Basu Laboratory Get in touch

Texas State University · San Marcos, Texas

Reading the structures
that shape life.

We study the language of RNA and DNA—uncovering how their structures guide cellular processes and how that knowledge can inspire new therapies.

Explore our research Meet the lab
Structural & functional nucleic acid biochemistry
01 / OUR RESEARCH

A closer look at the
molecules of life.

The Basu Laboratory investigates how the shape of nucleic acids influences the way cells work—and what happens when those processes go awry.

Led by Dr. Soumitra Basu in the Department of Chemistry and Biochemistry at Texas State University, our research brings structural biochemistry together with molecular biology and therapeutic design.

01

RNA & DNA structures

We investigate RNA and unusual DNA forms, including G-quadruplexes, to understand how molecular structure shapes biological function.

STRUCTURE
02

Cellular regulation

Our work explores the roles of nucleic acid structures in essential processes such as mRNA translation initiation and gene transcription.

MECHANISM
03

Therapeutic design

We design oligonucleotide-based drugs and advanced delivery systems, including spherical nucleic acids, to translate molecular insight into new possibilities.

TRANSLATION

From molecular insight to therapeutic possibility. Our collaborative research examines mechanisms relevant to Parkinson’s disease and explores approaches with potential in neurological disease and cancer.

02 / OUR COMMUNITY

People who move
science forward.

We’re proud of the scientists and scholars who have grown through the lab and carried their curiosity into universities, medicine, research, and industry.

Doctoral alumni 14

  1. Dr. Eric Sohenlen
  2. Dr. Mark Morris
  3. Dr. Debmalya Bhattacharya
  4. Dr. Mohammed Farhat Assistant Professor, South Eastern University, Sri Lanka
  5. Dr. Gayan Arachchilage Associate Director, biotech company
  6. Dr. Anthony Giovengo Chief Analytical Chemist, EPA
  7. Dr. Sumirtha Balaratnam Assistant Professor, Virginia Military Institute
  8. Dr. Prakash Kharel Assistant Professor, University of Kansas Medical Center
  9. Dr. Nathan Beals NYU Medical School
  10. Dr. Brad Popovich Assistant Professor, Concord University, WV
  11. Dr. Enamul Hoque Research Associate, Cleveland Clinic Foundation
  12. Dr. Thulasi Mahendran
  13. Dr. Mary Brintha Croos Assistant Professor, University of Mary Hardin-Baylor
  14. Dr. Mohammad Luftul Kabir Assistant Professor, KUET, Bangladesh

Master’s alumni 02

  1. Joseph Schonhoft PhD, Johns Hopkins University
  2. Abby Sewell Research Scientist, biotech company

Undergraduate honors 06

  1. Katherine Poinski MD, University of Toledo Medical School
  2. Firehwyat Acchamalaye MD, Hershey Medical Center, Penn State
  3. Katherine Wingate OD, Ohio State University; U.S. Army officer
  4. Alyssa Johnson PhD, Baylor College of Medicine
  5. Joram Rana PhD, Ohio State University
  6. Vishal Pokhrel PhD, Ohio State University

Career destinations are listed as provided by the lab.

03 / CONNECT

Curious about
what we do?

For inquiries about the lab and its research, get in touch with Dr. Basu at Texas State University.

Email the lab
VISIT / CONTACT

Department of Chemistry
& Biochemistry

Texas State University
San Marcos, TX 78666

(512) 245-3308 tcp79@txstate.edu Dr. Soumitra Basu’s faculty profile